Express Scripts Holding Co. (NASDAQ:ESRX) shares saw unusually-high trading volume on Tuesday . Approximately 5,452,890 shares changed hands during mid-day trading, an increase of 70% from the previous session’s volume of 3,198,363 shares.The stock last traded at $77.15 and had previously closed at $76.51.

ESRX has been the topic of a number of recent research reports. Bank of America Corp. reissued a “neutral” rating and issued a $82.00 target price on shares of Express Scripts Holding in a report on Tuesday, June 7th. Zacks Investment Research upgraded Express Scripts Holding from a “hold” rating to a “buy” rating and set a $85.00 price target on the stock in a research note on Tuesday, June 7th. Cowen and Company restated a “positive” rating and issued a $83.00 price target on shares of Express Scripts Holding in a research note on Wednesday, June 15th. Jefferies Group restated a “buy” rating on shares of Express Scripts Holding in a research note on Monday, July 4th. Finally, Credit Suisse Group AG restated a “buy” rating on shares of Express Scripts Holding in a research note on Monday, June 27th. Three research analysts have rated the stock with a sell rating, eleven have assigned a hold rating and eight have given a buy rating to the company’s stock. The company has a consensus rating of “Hold” and an average price target of $81.26.

The company has a 50 day moving average of $77.20 and a 200 day moving average of $73.30. The stock has a market capitalization of $48.62 billion and a P/E ratio of 19.06.

Express Scripts Holding (NASDAQ:ESRX) last issued its quarterly earnings results on Monday, July 25th. The company reported $1.57 earnings per share (EPS) for the quarter, meeting analysts’ consensus estimates of $1.57. During the same period in the previous year, the business posted $1.44 earnings per share. The firm had revenue of $25.20 billion for the quarter, compared to the consensus estimate of $25.42 billion. The business’s revenue for the quarter was down .9% compared to the same quarter last year. Equities research analysts anticipate that Express Scripts Holding Co. will post $6.38 EPS for the current fiscal year.

Several large investors recently added to or reduced their stakes in ESRX. Wafra Investment Advisory Group Inc. NY raised its stake in Express Scripts Holding by 975.2% in the fourth quarter. Wafra Investment Advisory Group Inc. NY now owns 165,049 shares of the company’s stock valued at $14,427,000 after buying an additional 149,699 shares in the last quarter. Schwab Charles Investment Management Inc. raised its stake in Express Scripts Holding by 12.2% in the fourth quarter. Schwab Charles Investment Management Inc. now owns 2,270,630 shares of the company’s stock valued at $198,476,000 after buying an additional 246,358 shares in the last quarter. Connor Clark & Lunn Investment Management Ltd. raised its stake in Express Scripts Holding by 8.3% in the fourth quarter. Connor Clark & Lunn Investment Management Ltd. now owns 209,673 shares of the company’s stock valued at $18,328,000 after buying an additional 16,000 shares in the last quarter. Calvert Investment Management Inc. bought a new stake in Express Scripts Holding during the fourth quarter valued at $3,110,000. Finally, American International Group Inc. raised its stake in Express Scripts Holding by 2.6% in the fourth quarter. American International Group Inc. now owns 372,766 shares of the company’s stock valued at $32,583,000 after buying an additional 9,278 shares in the last quarter.

Express Scripts, Inc is a pharmacy benefit management (PBM) company in North America, offering a range of services to its clients, which include health insurers, third-party administrators, employers, union-sponsored benefit plans, workers’ compensation plans and government health programs. It operates in two segments: PBM and Emerging Markets (EM).

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