Syndax Pharmaceuticals (NASDAQ: SNDX) is one of 45 publicly-traded companies in the “Biopharmaceuticals” industry, but how does it weigh in compared to its rivals? We will compare Syndax Pharmaceuticals to similar companies based on the strength of its analyst recommendations, risk, earnings, profitability, institutional ownership, valuation and dividends.

Institutional and Insider Ownership

70.7% of Syndax Pharmaceuticals shares are owned by institutional investors. Comparatively, 45.3% of shares of all “Biopharmaceuticals” companies are owned by institutional investors. 24.1% of Syndax Pharmaceuticals shares are owned by insiders. Comparatively, 13.9% of shares of all “Biopharmaceuticals” companies are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Analyst Recommendations

This is a breakdown of current recommendations and price targets for Syndax Pharmaceuticals and its rivals, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Syndax Pharmaceuticals 0 0 10 0 3.00
Syndax Pharmaceuticals Competitors 190 912 1685 67 2.57

Syndax Pharmaceuticals presently has a consensus target price of $24.88, indicating a potential upside of 112.79%. As a group, “Biopharmaceuticals” companies have a potential upside of 6.19%. Given Syndax Pharmaceuticals’ stronger consensus rating and higher possible upside, equities analysts plainly believe Syndax Pharmaceuticals is more favorable than its rivals.

Volatility and Risk

Syndax Pharmaceuticals has a beta of 4.78, indicating that its share price is 378% more volatile than the S&P 500. Comparatively, Syndax Pharmaceuticals’ rivals have a beta of 1.24, indicating that their average share price is 24% more volatile than the S&P 500.


This table compares Syndax Pharmaceuticals and its rivals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Syndax Pharmaceuticals -4,294.59% -58.23% -45.65%
Syndax Pharmaceuticals Competitors -13,072.07% 230.44% -22.70%

Earnings and Valuation

This table compares Syndax Pharmaceuticals and its rivals revenue, earnings per share and valuation.

Gross Revenue EBITDA Price/Earnings Ratio
Syndax Pharmaceuticals $1.22 million -$53.19 million -4.12
Syndax Pharmaceuticals Competitors $579.31 million $242.01 million -6.33

Syndax Pharmaceuticals’ rivals have higher revenue and earnings than Syndax Pharmaceuticals. Syndax Pharmaceuticals is trading at a higher price-to-earnings ratio than its rivals, indicating that it is currently more expensive than other companies in its industry.


Syndax Pharmaceuticals beats its rivals on 7 of the 12 factors compared.

About Syndax Pharmaceuticals

Syndax Pharmaceuticals, Inc (Syndax) is a clinical stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. The Company’s product candidate, entinostat, which was granted Breakthrough Therapy designation by the FDA following positive results from its Phase IIb clinical trial, ENCORE 301, is being evaluated in a Phase III clinical trial for advanced hormone receptor positive breast cancer. It is developing entinostat, which has direct effects on both cancer cells and immune regulatory cells, and SNDX-6352, an anti-CSF-1R monoclonal antibody, to enhance the body’s immune response on tumors that have shown sensitivity to immunotherapy. Entinostat is being evaluated as a combination therapeutic in Phase Ib/II clinical trials with Merck & Co., Inc. for non-small cell lung cancer and melanoma, with Genentech, Inc. for TNBC, and with Pfizer Inc. and Merck KGaA, Darmstadt, Germany, for ovarian cancer.

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