Miragen Therapeutics (NASDAQ: MGEN) and Cannabis Science (OTCMKTS:CBIS) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their risk, institutional ownership, dividends, valuation, earnings, profitability and analyst recommendations.


This table compares Miragen Therapeutics and Cannabis Science’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Miragen Therapeutics -720.38% -80.31% -64.59%
Cannabis Science -953,196.00% N/A -380.46%

Risk and Volatility

Miragen Therapeutics has a beta of 1.89, meaning that its share price is 89% more volatile than the S&P 500. Comparatively, Cannabis Science has a beta of -3.62, meaning that its share price is 462% less volatile than the S&P 500.

Insider and Institutional Ownership

22.6% of Miragen Therapeutics shares are held by institutional investors. 44.4% of Miragen Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Analyst Ratings

This is a breakdown of current ratings for Miragen Therapeutics and Cannabis Science, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Miragen Therapeutics 0 0 3 0 3.00
Cannabis Science 0 0 0 0 N/A

Miragen Therapeutics presently has a consensus price target of $24.00, suggesting a potential upside of 217.88%. Given Miragen Therapeutics’ higher probable upside, equities research analysts plainly believe Miragen Therapeutics is more favorable than Cannabis Science.

Earnings and Valuation

This table compares Miragen Therapeutics and Cannabis Science’s gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Miragen Therapeutics $3.34 million 50.43 -$12.67 million ($8.93) -0.85
Cannabis Science N/A N/A N/A N/A N/A

Cannabis Science has lower revenue, but higher earnings than Miragen Therapeutics.


Miragen Therapeutics beats Cannabis Science on 8 of the 9 factors compared between the two stocks.

About Miragen Therapeutics

Signal Genetics, Inc. is a commercial stage, molecular genetic diagnostic company. The Company is focused on providing diagnostic services that help physicians to make decisions concerning the care of cancer patients. The Company’s diagnostic service is the Myeloma Prognostic Risk Signature (MyPRS) test. The MyPRS test is a microarray-based gene expression profile (GEP), assay that measures the expression level of specific genes and groups of genes that are designed to predict an individual’s long-term clinical outcome/prognosis, giving a basis for personalized treatment options. The Company’s MyPRS test provides a whole-genomic expression profile of a patient’s multiple myeloma (MM). The Company offers MyPRS test in its laboratory located in Little Rock, Arkansas. The Company is licensed to sell its test in all 50 states.

About Cannabis Science

Cannabis Science, Inc. is engaged in medical marijuana research and development. The Company works on phytocannabinoid science targeting critical illnesses, and adheres to scientific methodologies to develop, produce and commercialize phytocannabinoid-based pharmaceutical products. The Company is involved in the creation of cannabis-based medicines, both with and without psychoactive properties, to treat disease and the symptoms of disease, as well as for general health maintenance. The Company focuses on the development of governmentally approved pharmaceuticals, including CS-TATI1, CS-S/BCC-1 and neurological therapy under study or development. The Company’s subsidiaries include Cannabis Science BV and Cannabis Science International Holding BV.

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