BioLife Solutions (NASDAQ: RSLS) and Reshape Lifesciences (NASDAQ:RSLS) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their dividends, analyst recommendations, earnings, risk, profitability, valuation and institutional ownership.

Volatility and Risk

BioLife Solutions has a beta of 0.64, suggesting that its stock price is 36% less volatile than the S&P 500. Comparatively, Reshape Lifesciences has a beta of 2.2, suggesting that its stock price is 120% more volatile than the S&P 500.


This table compares BioLife Solutions and Reshape Lifesciences’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
BioLife Solutions 1.76% 2.24% 1.92%
Reshape Lifesciences -2,397.35% -70.96% -60.41%

Analyst Recommendations

This is a breakdown of recent ratings and price targets for BioLife Solutions and Reshape Lifesciences, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioLife Solutions 0 0 3 0 3.00
Reshape Lifesciences 0 1 0 0 2.00

BioLife Solutions presently has a consensus target price of $17.67, suggesting a potential downside of 30.65%. Given BioLife Solutions’ stronger consensus rating and higher probable upside, equities analysts plainly believe BioLife Solutions is more favorable than Reshape Lifesciences.

Insider & Institutional Ownership

27.8% of BioLife Solutions shares are owned by institutional investors. 38.5% of BioLife Solutions shares are owned by company insiders. Comparatively, 9.2% of Reshape Lifesciences shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Valuation and Earnings

This table compares BioLife Solutions and Reshape Lifesciences’ gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
BioLife Solutions $11.02 million 38.05 -$2.51 million ($0.21) -121.31
Reshape Lifesciences $1.29 million 0.45 -$33.81 million ($47.68) 0.00

BioLife Solutions has higher revenue and earnings than Reshape Lifesciences. BioLife Solutions is trading at a lower price-to-earnings ratio than Reshape Lifesciences, indicating that it is currently the more affordable of the two stocks.


BioLife Solutions beats Reshape Lifesciences on 12 of the 14 factors compared between the two stocks.

BioLife Solutions Company Profile

BioLife Solutions, Inc. develops, manufactures, and markets patented tissue hypothermic storage and cryopreservation freeze media products for cells, tissues, and organs in the United States. Its products are serum-free and protein-free solutions, which are formulated to reduce preservation-induced, and delayed-onset cell damage and death. The company offers HypoThermosol FRS, a hypothermic storage and shipping media product to mitigate temperature-induced molecular cell stress responses that occur during chilling and re-warming of biologics, intermediate products, and final cell products intended for research and clinical applications; and CryoStor cryopreservation freeze media products to mitigate temperature-induced molecular cell stress responses during freezing and thawing. It also provides BloodStor freeze media products, such as BloodStor 55-5 and BloodStor 100 for cryopreservation of stem and other cells isolated from umbilical cord and peripheral blood, and bone marrow; and cell thawing media, which offers Dextran and saline for washing cryopreserved cells and tissues to dilute or remove cryoprotectants. In addition, the company provides custom product formulation and packaging services; and contract aseptic manufacturing formulation, filling, and finishing services for liquid media products. It markets its products to the regenerative medicine, bio-banking, and drug discovery markets, including hospital-based stem cell transplant centers, pharmaceutical companies, cord blood and adult stem cell banks, and hair transplant centers, as well as suppliers of cells to the drug discovery, toxicology testing, and diagnostic markets. The company markets and sells its products directly using its sales force, as well as through; and through various regional distributors. BioLife Solutions, Inc. was founded in 1987 and is headquartered in Bothell, Washington.

Reshape Lifesciences Company Profile

ReShape Lifesciences Inc., a medical device company, focuses on the design and development of devices that use neuroblocking technology to treat obesity, metabolic diseases, and other gastrointestinal disorders. Its proprietary neuroblocking technology, vBloc Therapy is designed to intermittently block the vagus nerve using electrical impulses. The company's product portfolio includes ReShape vBloc, a therapy that enables patients to feel full and eat less by intermittently blocking hunger signals on the vagus nerve; and ReShape Balloon system that uses balloon technology designed to take up room in the stomach to enable people lose weight. Its product portfolio also comprises ReShape Vest system, an investigational, minimally invasive, laparoscopically implanted medical device that wraps around the stomach to enable weight loss in obese and morbidly obese patients without permanently changing patient anatomy. The company was formerly known as EnteroMedics Inc. and changed its name to ReShape Lifesciences Inc. in October 2017. ReShape Lifesciences Inc. was founded in 2002 and is headquartered in San Clemente, California.

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