Vascular Biogenics (NASDAQ: MCRB) and Seres Therapeutics (NASDAQ:MCRB) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their dividends, risk, analyst recommendations, profitability, earnings, institutional ownership and valuation.

Analyst Recommendations

This is a summary of recent ratings and target prices for Vascular Biogenics and Seres Therapeutics, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vascular Biogenics 0 4 0 0 2.00
Seres Therapeutics 1 0 5 0 2.67

Vascular Biogenics currently has a consensus price target of $3.33, indicating a potential upside of 108.33%. Seres Therapeutics has a consensus price target of $19.25, indicating a potential upside of 146.48%. Given Seres Therapeutics’ stronger consensus rating and higher possible upside, analysts clearly believe Seres Therapeutics is more favorable than Vascular Biogenics.

Profitability

This table compares Vascular Biogenics and Seres Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Vascular Biogenics N/A -23.24% -19.85%
Seres Therapeutics -264.31% -256.24% -52.81%

Volatility & Risk

Vascular Biogenics has a beta of -1.87, meaning that its stock price is 287% less volatile than the S&P 500. Comparatively, Seres Therapeutics has a beta of 0.54, meaning that its stock price is 46% less volatile than the S&P 500.

Earnings and Valuation

This table compares Vascular Biogenics and Seres Therapeutics’ revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Vascular Biogenics $13.86 million 3.46 -$10.13 million ($0.37) -4.32
Seres Therapeutics $32.10 million 9.93 -$89.38 million ($2.21) -3.53

Vascular Biogenics has higher earnings, but lower revenue than Seres Therapeutics. Vascular Biogenics is trading at a lower price-to-earnings ratio than Seres Therapeutics, indicating that it is currently the more affordable of the two stocks.

Insider and Institutional Ownership

18.9% of Vascular Biogenics shares are owned by institutional investors. Comparatively, 78.0% of Seres Therapeutics shares are owned by institutional investors. 37.1% of Seres Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Summary

Seres Therapeutics beats Vascular Biogenics on 9 of the 14 factors compared between the two stocks.

About Vascular Biogenics

Vascular Biogenics Ltd., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of treatments for cancer. The company's program is based on its proprietary vascular targeting system platform technology, which utilizes genetically targeted therapy to destroy newly formed or angiogenic blood vessels. Its lead product candidate is VB-111, a gene-based biologic that is in Phase III clinical trials for the treatment of recurrent glioblastoma, an aggressive form of brain cancer; and in Phase III clinical trials for recurrent platinum-resistant ovarian cancer, as well as for Phase II clinical trials for iodine-resistant differentiated thyroid cancer. The company is also developing VB-111, which is in Phase I clinical trials for the treatment of patients with various types of advanced metastatic cancer types, including thyroid cancer, neuroendocrine cancer, renal cell carcinoma, and lung cancer. In addition, it is developing VB-511, an anti-angiogenic candidate for oncology; VB-211 and VB-411, which are pro-angiogenic candidates for the treatment of peripheral vascular diseases; VB-201, a Lecinoxoid-based compound for the control of chronic inflammatory disorders; and VB-600 that is in pre-clinical stage for targeting of MOSPD2 for immuno-oncology and anti-inflammatory applications. The company was formerly known as Medicard Ltd. and changed its name to Vascular Biogenics Ltd. in January 2003. Vascular Biogenics Ltd. was founded in 2000 and is headquartered in Modi'in, Israel.

About Seres Therapeutics

Seres Therapeutics, Inc., a microbiome therapeutics platform company, engages in developing biological drugs designed to restore health by repairing the function of a dysbiotic microbiome. Its lead product candidate is SER-109, a bacterial spore ecology, which is in Phase III clinical study to treat multiply recurrent Clostridium difficile infection (CDI). The company is also developing SER-287 that is in Phase Ib clinical study in patients with mild-to-moderate ulcerative colitis; and SER-262, a multi-strain Ecobiotic microbiome therapeutic candidate, which is in Phase Ib study in patients with primary CDI. In addition, its product candidates in pre-clinical development comprise SER-301, an Ecobiotic microbiome therapeutic candidate for the treatment of inflammatory bowel disease; SER-401 for use with checkpoint inhibitors in patients with solid tumors; and SER-155, an Ecobiotic microbiome therapeutic candidate for the prevention of transplant-related mortality. Seres Therapeutics, Inc. has a strategic collaboration with Nestle Health Science and Memorial Sloan Kettering Cancer Center. The company was formerly known as Seres Health, Inc. and changed its name to Seres Therapeutics, Inc. in May 2015. Seres Therapeutics, Inc. was founded in 2010 and is headquartered in Cambridge, Massachusetts.

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