Pharmaxis (OTCMKTS:PXSLY – Get Free Report) and Synaptogenix (NASDAQ:TAOX – Get Free Report) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, analyst recommendations, dividends, institutional ownership, earnings, valuation and profitability.
Analyst Recommendations
This is a breakdown of current recommendations for Pharmaxis and Synaptogenix, as reported by MarketBeat.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Pharmaxis | 0 | 0 | 0 | 0 | 0.00 |
| Synaptogenix | 1 | 0 | 0 | 0 | 1.00 |
Earnings & Valuation
This table compares Pharmaxis and Synaptogenix”s gross revenue, earnings per share and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Pharmaxis | $8.75 million | 3.03 | -$9.36 million | N/A | N/A |
| Synaptogenix | N/A | N/A | -$12.77 million | ($20.16) | -0.27 |
Pharmaxis has higher revenue and earnings than Synaptogenix.
Volatility & Risk
Pharmaxis has a beta of 1.22, indicating that its share price is 22% more volatile than the S&P 500. Comparatively, Synaptogenix has a beta of 1.98, indicating that its share price is 98% more volatile than the S&P 500.
Institutional and Insider Ownership
10.3% of Synaptogenix shares are owned by institutional investors. 2.7% of Synaptogenix shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.
Profitability
This table compares Pharmaxis and Synaptogenix’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Pharmaxis | N/A | N/A | N/A |
| Synaptogenix | N/A | -240.92% | -150.03% |
About Pharmaxis
Pharmaxis Ltd engages in the research, development, and commercialization of healthcare products for the treatment of fibrotic and inflammatory diseases worldwide. The company operates through two segments, Mannitol business, and New Drug Development. It offers Bronchitol, an inhaled dry powder for the treatment of cystic fibrosis; and Aridol, an airways inflammation test that is used to identify twitchy or hyper-responsive airways, as well as to assist in diagnosing and managing asthma. The company's product pipeline consists of amine oxidase inhibitors comprising semicarbazide-sensitive amine oxidase for diabetic retinopathy; selective lysyl oxidase like inhibitors targeting chronic fibrotic diseases, such as NASH, pulmonary fibrosis, kidney fibrosis, and cardiac fibrosis; and pan-lysyl oxidase inhibitors targeting severe fibrotic indications, which includes cancers and scarring. It is also developing Orbital, a dry powder inhaler to deliver high drug doses to lungs. Pharmaxis Ltd was founded in 1998 and is headquartered in Frenchs Forest, Australia.
About Synaptogenix
Synaptogenix, Inc. operates as a biopharmaceutical company with product candidates in pre-clinical and clinical development. It focuses on developing a product platform based upon a drug candidate called Bryostatin-1 for the treatment of Alzheimer’s disease. The company is also evaluating therapeutic applications of bryostatin for other neurodegenerative or cognitive diseases and dysfunctions, such as fragile X syndrome, multiple sclerosis, and Niemann-pick type C disease. Synaptogenix, Inc. has licensing agreements with Stanford University; Icahn School of Medicine at Mount Sinai; and The Board of Trustees of the Leland Stanford Junior University. The company was incorporated in 2012 and is headquartered in New York, New York.
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