Astellas Pharma (OTCMKTS:ALPMY – Get Free Report) and Bristol Myers Squibb (NYSE:BMY – Get Free Report) are both large-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their profitability, institutional ownership, analyst recommendations, dividends, risk, earnings and valuation.
Profitability
This table compares Astellas Pharma and Bristol Myers Squibb’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Astellas Pharma | 16.01% | 25.79% | 12.87% |
| Bristol Myers Squibb | 18.87% | 66.90% | 14.74% |
Valuation and Earnings
This table compares Astellas Pharma and Bristol Myers Squibb”s top-line revenue, earnings per share and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Astellas Pharma | $14.21 billion | 2.03 | $1.83 billion | $1.31 | 12.18 |
| Bristol Myers Squibb | $48.19 billion | 2.61 | $7.05 billion | $4.54 | 13.56 |
Bristol Myers Squibb has higher revenue and earnings than Astellas Pharma. Astellas Pharma is trading at a lower price-to-earnings ratio than Bristol Myers Squibb, indicating that it is currently the more affordable of the two stocks.
Analyst Ratings
This is a summary of recent recommendations and price targets for Astellas Pharma and Bristol Myers Squibb, as reported by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Astellas Pharma | 0 | 3 | 0 | 1 | 2.50 |
| Bristol Myers Squibb | 1 | 16 | 11 | 2 | 2.47 |
Bristol Myers Squibb has a consensus price target of $64.88, suggesting a potential upside of 5.37%. Given Bristol Myers Squibb’s higher possible upside, analysts plainly believe Bristol Myers Squibb is more favorable than Astellas Pharma.
Insider and Institutional Ownership
76.4% of Bristol Myers Squibb shares are held by institutional investors. 0.1% of Bristol Myers Squibb shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.
Volatility and Risk
Astellas Pharma has a beta of 0.08, meaning that its stock price is 92% less volatile than the S&P 500. Comparatively, Bristol Myers Squibb has a beta of 0.19, meaning that its stock price is 81% less volatile than the S&P 500.
Dividends
Astellas Pharma pays an annual dividend of $0.29 per share and has a dividend yield of 1.8%. Bristol Myers Squibb pays an annual dividend of $2.52 per share and has a dividend yield of 4.1%. Astellas Pharma pays out 22.1% of its earnings in the form of a dividend. Bristol Myers Squibb pays out 55.5% of its earnings in the form of a dividend. Both companies have healthy payout ratios and should be able to cover their dividend payments with earnings for the next several years. Bristol Myers Squibb has raised its dividend for 17 consecutive years. Bristol Myers Squibb is clearly the better dividend stock, given its higher yield and longer track record of dividend growth.
Summary
Bristol Myers Squibb beats Astellas Pharma on 16 of the 18 factors compared between the two stocks.
About Astellas Pharma
Astellas Pharma Inc. manufactures, markets, and imports and exports pharmaceuticals in Japan and internationally. The company provides XTANDI, a treatment for prostate cancer; XOSPATA, a treatment for patients who have relapsed or refractory acute myeloid leukemia with a FLT3 mutation; and PADCEV, a treatment for patients with metastatic urothelial cancer. It also offers Evrenzo, a treatment for anemia associated with chronic kidney disease; Betanis/Myrabetriq/BETMIGA, a treatment for overactive bladder; and Prograf and Advagraf/Graceptor/ASTAGRAF XL immunosuppressants. Th company has a research collaboration with Vivtex Corporation to evaluate Vivtex’s GI-ORIS screening and formulation platform technology to support the development of novel and oral versions of a therapeutic candidate provided by Astellas; and a partnership agreement with Roche Diabetes Care Japan Co., Ltd. to develop and commercialize integrated diabetes self-management solution. The company was founded in 1923 and is headquartered in Tokyo, Japan.
About Bristol Myers Squibb
Bristol-Myers Squibb Company discovers, develops, licenses, manufactures, markets, distributes, and sells biopharmaceutical products worldwide. It offers products for hematology, oncology, cardiovascular, immunology, fibrotic, and neuroscience diseases. The company's products include Eliquis for reduction in risk of stroke/systemic embolism in non-valvular atrial fibrillation, and for the treatment of DVT/PE; Opdivo for various anti-cancer indications, including bladder, blood, CRC, head and neck, RCC, HCC, lung, melanoma, MPM, stomach and esophageal cancer; Pomalyst/Imnovid for multiple myeloma; Orencia for active rheumatoid arthritis and psoriatic arthritis; and Sprycel for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia. It also provides Yervoy for the treatment of patients with unresectable or metastatic melanoma; Empliciti for the treatment of multiple myeloma; Abecma for the treatment of relapsed or refractory multiple myeloma; Reblozyl for the treatment of anemia; Opdualag for the treatment of unresectable or metastatic melanoma; and Zeposia to treat relapsing forms of multiple sclerosis. In addition, the company offers Breyanzi for the treatment of relapsed or refractory large B-cell lymphoma; Onureg for the treatment of AML; Inrebic for the treatment of myelofibrosis; Camzyos for the treatment of symptomatic obstructive HCM to enhance functional capacity and symptom; Sotyktu for the treatment of moderate-to-severe plaque psoriasis; Augtyro for the treatment of locally advanced or metastatic ROS1-positive NSCLC; Revlimid, an oral immunomodulatory drug for the treatment of multiple myeloma; and Abraxane to treat breast cancer, NSCLC and pancreatic cancer. It sells products to wholesalers, distributors, pharmacies, retailers, hospitals, clinics, and government agencies. The company was formerly known as Bristol-Myers Company. Bristol-Myers Squibb Company was founded in 1887 and is headquartered in Princeton, New Jersey.
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