Harmony Biosciences (NASDAQ:HRMY – Get Free Report) and Astellas Pharma (OTCMKTS:ALPMY – Get Free Report) are both healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their institutional ownership, valuation, analyst recommendations, dividends, earnings, risk and profitability.
Risk & Volatility
Harmony Biosciences has a beta of 1, meaning that its share price has a similar volatility profile to the S&P 500.Comparatively, Astellas Pharma has a beta of 0.06, meaning that its share price is 94% less volatile than the S&P 500.
Institutional & Insider Ownership
86.2% of Harmony Biosciences shares are held by institutional investors. 11.0% of Harmony Biosciences shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.
Earnings and Valuation
This table compares Harmony Biosciences and Astellas Pharma”s gross revenue, earnings per share and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Harmony Biosciences | $868.45 million | 2.25 | $158.69 million | $3.02 | 11.12 |
| Astellas Pharma | $14.21 billion | 2.09 | $1.83 billion | $1.36 | 12.04 |
Astellas Pharma has higher revenue and earnings than Harmony Biosciences. Harmony Biosciences is trading at a lower price-to-earnings ratio than Astellas Pharma, indicating that it is currently the more affordable of the two stocks.
Profitability
This table compares Harmony Biosciences and Astellas Pharma’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Harmony Biosciences | 18.05% | 18.55% | 13.24% |
| Astellas Pharma | 16.18% | 26.13% | 13.32% |
Analyst Ratings
This is a breakdown of current ratings and recommmendations for Harmony Biosciences and Astellas Pharma, as reported by MarketBeat.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Harmony Biosciences | 1 | 4 | 7 | 1 | 2.62 |
| Astellas Pharma | 0 | 3 | 0 | 1 | 2.50 |
Harmony Biosciences currently has a consensus target price of $48.00, suggesting a potential upside of 42.89%. Given Harmony Biosciences’ stronger consensus rating and higher probable upside, equities research analysts plainly believe Harmony Biosciences is more favorable than Astellas Pharma.
Summary
Harmony Biosciences beats Astellas Pharma on 9 of the 14 factors compared between the two stocks.
About Harmony Biosciences
Harmony Biosciences is a biopharmaceutical company focused on developing and commercializing treatments for people living with rare neurological diseases. The company’s work centers on therapies intended to address significant unmet medical needs. Its lead product, WAKIX (pitolisant), is approved in the United States to treat excessive daytime sleepiness or cataplexy in adults and pediatric patients aged 6 years and older with narcolepsy. Harmony launched WAKIX in the United States in 2019. Founded in 2017 and headquartered in Plymouth Meeting, Pennsylvania, Harmony primarily serves the U.S. market.
About Astellas Pharma
Astellas Pharma Inc. is a Japan-based pharmaceutical company that researches, develops, manufactures and markets prescription medicines. The company was formed in 2005 through the merger of Yamanouchi Pharmaceutical and Fujisawa Pharmaceutical, and is headquartered in Tokyo. Astellas develops treatments across areas including oncology, urology, immunology and women’s health. Its medicines include Xtandi (enzalutamide), used to treat certain forms of prostate cancer, and Prograf (tacrolimus), an immunosuppressant used in organ transplantation.
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